Research Article
Voltammetric Assessment of Paracetamol on a CuONPs – MWCNTs Modified Glassy Carbon Electrode
Rajesh Hegde*
,
Vishwanatha Poojary,
Kiran Kamath
Issue:
Volume 13, Issue 3, September 2024
Pages:
59-65
Received:
19 June 2024
Accepted:
18 July 2024
Published:
15 August 2024
Abstract: In this work, an electrochemical sensor using differential pulse voltammetric method for the assessment of antipyretic and analgesic drug, paracetamol was developed. The CuO nanoparticles were synthesized and characterized. A glassy carbon electrode (GCE) fabricated with the suspension of CuO nanoparticles (CuONPs) and multi-walled carbon nanotubes (MWCNTs) were used. The fabricated electrode was characterized using Potassium ferricyanide as a redox probe, which showed increase in the electro active area in the modified electrode. The modified electrode showed improved anodic peak current enhancement in phosphate buffer solution. The consequence of pH of supporting electrolyte and amount of nanoparticles suspension were investigated at a physiological pH of 7.4. Using differential pulse voltammetry, the fabricated electrode showed linear dynamic range from 9 to 160 nM of paracetamol concentration. From the calibration plot, the computed detection limit was 5.06nM and quantification limit was16.88 nM. The developed method was checked for its reproducibility and assay during a day and intraday as well and the results were good with permitted range of errors. The developed process was fruitfully applied to detect paracetamol in pharmaceutical formulations.
Abstract: In this work, an electrochemical sensor using differential pulse voltammetric method for the assessment of antipyretic and analgesic drug, paracetamol was developed. The CuO nanoparticles were synthesized and characterized. A glassy carbon electrode (GCE) fabricated with the suspension of CuO nanoparticles (CuONPs) and multi-walled carbon nanotubes...
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Review Article
Perspective—Concerning a New Mechanistic Model Toward the Catalytic Ammonia Synthesis
Youyi Sun*
Issue:
Volume 13, Issue 3, September 2024
Pages:
66-71
Received:
6 July 2024
Accepted:
23 July 2024
Published:
15 August 2024
Abstract: A reasonable catalytic mechanistic model should refer to a widely range of catalytic reaction. We believe that all types of catalytic reaction on heterogeneous catalysis should follow a general mechanism, and it is our opinion that with the hall-filled valence orbitals, the atom of catalysts could convert the reactant into reactive radical and/or support the formation of new chemical bond between two reactants via radical dimerization. In our recent publications this new mechanistic model on the catalytic Fischer-Tropsch reaction (the conversion of CO and H2 to hydrocarbons), electrochemical hydrogen evolution reactions, and hydrogen combustion in various metal catalysts is discussed, and which seems to provide a reasonable interpretation to those catalytic reactions. In the present work it is discussed that this new mechanistic model is suitable to the Haber-Bosch process (catalytic ammonia synthesis) on various transition metal catalysts, and a reasonable explanation is provided on the catalytic property of various transition metal for ammonia synthesis.
Abstract: A reasonable catalytic mechanistic model should refer to a widely range of catalytic reaction. We believe that all types of catalytic reaction on heterogeneous catalysis should follow a general mechanism, and it is our opinion that with the hall-filled valence orbitals, the atom of catalysts could convert the reactant into reactive radical and/or s...
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